期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

支气管哮喘靶向治疗的新进展 被引量：5

下载PDF
导出
作者 张丽娜 陈萍
机构地区 第四军医大学西京医院呼吸内科 沈阳军区总医院呼吸内科
出处 《中国呼吸与危重监护杂志》 CAS 2009年第4期411-414,共4页 Chinese Journal of Respiratory and Critical Care Medicine
基金 全军"十一五"科研课题(编号:06MA050)
关键词 支气管哮喘 靶向治疗 糖皮质激素治疗 气道上皮细胞 慢性炎症性疾病 嗜酸粒细胞 控制症状 T淋巴细胞
分类号 R562.25 [医药卫生—呼吸系统] R730.5 [医药卫生—肿瘤]
  • 相关文献

参考文献37

  • 1Borish LC,Nelson HS,Lanz MJ,et al.Interleukin-4 Receptor in Moderate Atopic Asthma:a phase Ⅰ/Ⅱ randomized,placebocontrolled trial.Am J Respir Crit Care Med,1999,160:1816-1823.
  • 2Borish LC,Nelson HS,Corren J,et al.Efficacy of soluble IL-4 receptor for the treatment of adults with asthma.J Allergy Clin Immunol,2001,107:963-970.
  • 3Kips JC,O' Connor B J,Langley SJ,et al.Effect of SCH55700,a humanized anti-human intedeukin-5 antibody,in severe persistent asthma:a pilot study.Am J Respir Crit Care Med,2003,167:1655-1659.
  • 4Buttner C,Lun A,Splettstoesser T,et al.Monoclonal antiinterleukin-5 treatment suppresses eesinophil but not T-cell function.Eur Respir J,2003,21:799-803.
  • 5Leckie MJ,ten Brinke A,Khan J,et al.Effects of an intedeukin-5 blocking monoclonal antibody on eosinophils,airway hyperresponsiveness,and the late asthmatic response.Lancet,2000,356:2144-2148.
  • 6Bree A,Sehlerman FJ,Wadanoli M,et al.IL-13 blockade reduces lung inflammation after Ascaris suum challenge in eynomolgus monkeys.J Allergy Clin Irnmunol,2007,119:1251-1257.
  • 7Blanchard C,Mishra A,Saito-Akei H,et dal.Inhibition of human interleukin-13-induced respiratory and oesephageal inflammation by anti-human-interleukin-13 antibody (CAT-354).Clin Exp Allergy,2005,35:1096-1103.
  • 8Busse WW,lsrael E,Nelson HS,et al.Daclizumab improves asthma control in patients with moderate to severe persistent asthma:a randomized,controlled trial.Am J Respir Crit Care Med,2008,178:1002-1008.
  • 9Krieg AM.Therapeutic potential of Toll-like receptor 9 activation.Nat Rev Drug Discov,2006,5:471-484.
  • 10Gauvreau GM,Hessel EM,Boulet LP,et al.Immunostimulatory sequences regulate interferon-inducible genes but not allergic airway responses.Am J Respir Crit Care Med,2006,174:15-20.

二级参考文献44

  • 1萨姆布鲁克 刘安.从聚丙烯酰胺中分离DNA片段.分子克隆实验指南（第2版）[M].北京:科学出版社,1996.332-333.
  • 2Zheng W, Flavell RA. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4^+ T ceils. Cell,1997, 89(4):587-596.
  • 3Ting CN, Olson MC, Barton KP, et al. Transcription factor GATA-3 is reqired for development of the T-cell Lineage. Nature, 1996, 384(6608):474 - 478.
  • 4Nakamura Y, Ghaffar O, Olivenstein R, et al. Gene expression of GATA-3 transcription factor is increased in atopic asthma. J Allergy Clin Immunol, 1999, 103(2):215-222.
  • 5Tanaka M, Nyce JW. Respirable antisense oligonucleotides: a new drug class for respiratory disease. Respir Res, 2001,2(1):5 - 9.
  • 6Maddox L,Schwartz DA. The pathophysioiogy of asthma. Annu Rev Med, 2002,53: 477-498.
  • 7Lawson JA, Senthilselvan A. Asthma epidemiology: has the crisis passed?. Curr Opin Pulm Med, 2005,11 : 79-84.
  • 8Miescher SM, Vogel M. Molecular aspects of allergy. Mol Aspects Med, 2002,23 : 413-462.
  • 9Lambrecht BN,Hammad H. Taking our breath away: dendritic cells in the pathogenesis of asthma. Nat Rev Immunol, 2003,3:994-1003.
  • 10Temann UA, Geba GP, Rankin JA, et al. Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness. J Exp Med, 1998,188 : 1307-1320.

共引文献1

同被引文献19

引证文献5

二级引证文献18

中国呼吸与危重监护杂志
2009年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部