原发性肝癌自发性破裂的危险因素多因素分析

Analysis of risk factors for spontaneous rupture of primary hepatic carcinoma

目的探讨原发性肝癌自发性破裂的危险因素。方法将1999年1月—2008年12月间收治的原发性肝癌自发性破裂的31例患者(破裂组)与同期住院的未发生破裂的肝癌患者中随机抽出的31例患者(对照组)进行临床资料的回顾分析与对比。结果单因素及多因素分析显示,与原发性肝癌自发性破裂有关的有因素有3个,即APTT,HBeAg,肿瘤突出肝表面的最大突出高度。结论APTT,HBeAg及肿瘤突出肝表面的最大高度是肝癌自发性破裂的独立危险因素。

Objective To study the risk factors for spontaneous rupture of primary hepatic carcinoma. Methods The clinical data of 31 patients with spontaneous rupture of primary hepatic cancer admitted to our hospital from Jan 1999 to Dec. 2008 were retrospectively analyzed, and compared with 31 randomly selected concurrent patients without rapture of HCC. Results Three factors were shown to be the risk factors for spontaneous rupture of primary hepatic carcinoma. Those were APTT, HBeAg and the greatest height of tumor protrusion above the surface of liver. Conclusions APTT, HBeAg and the greatest height of tumor protrusion above the surface of liver are risk factors for spontaneous rupture of orimarv hepatic carcinoma.