摘要
目的回顾性分析10例羊水栓塞(AFE)致弥漫性血管内凝血(DIC)的临床处理,评价急诊子宫切除的作用与意义。方法对2002年2月-2009年3月10例AFE并DIC患者,给予大剂量肾上腺皮质激素、应用适量的肝素、恰当时机切除子宫、技术条件具备时加行双侧髂内动脉结扎术。结果全子宫切除10例,存活者7例;死亡3例,其中2例于术后2 d并多脏器功能衰竭死亡,1例术后45 d并肺栓塞死亡。结论AFE并DIC患者抢救成功的关键为识别早期症状,阻断羊水栓塞病理生理进展;恰当处理可增加抢救成功率。
Objective To analyze clinical management of amniotic fluid embolism （AFE） with disseminated intravascular coagulation（DIC） ;to summarize and evaluate effect and significance of emergency hysterectomies. Methods Ten cases of AFE and DIC from February 2002 to March 2009, with larger dose of corticosteroid hormones, heparin application,total hysterectomy in time and hypogastric artery ligation if necessary. Results Ten cases received hysterectomy, 7 case survived,3 cases died. One case died of pulmonary embolism in 45 days after operation and two cases died of MDOS in 2 days after operation. Conclusion The critical treatment of AFE and DIC consists of： identification of the precursory signs, and interrupt pathophysiology of AFE. Proper treatment could increase the successful rescue rate.
出处
《江西医学院学报》
CAS
2009年第6期62-64,共3页
Acta Academiae Medicinae Jiangxi
关键词
羊水栓塞
弥漫性血管内凝血
全子宫切除
amuiotic fluid embolism
disseminated intravascular coagulation
total hysterectomy
