摘要
目的观察雷米普利联合氨氯地平对老年性高血压患者血压的影响。方法194例老年性高血压患者随机分为治疗组(联合应用雷米普利与氨氯地平组)和对照组(雷米普利组),治疗期间每周至少测量血压1次(OBP),治疗前和治疗24周后进行动态血压监测(ABP)。结果二者联合用药可以有效降低血压,治疗组与对照组比较差异有统计学意义(P<0.05),二组治疗后与治疗前比较也有显著性差异(P<0.05)。结论联合使用雷米普利和氨氯地平与单独使用雷米普利可以有效的控制老年性高血压患者的血压,但二者联合降压疗效优于雷米普利,且总体耐受性好于雷米普利。
Objective To study the efficacy of treating age-related hypertensive patients using Ramipril combined with Amlodipine. Methods 194 cases of age-related hypertensive patients were randomly divided into the treatment group（using Ramipril combined with Amlodipine） and the control group（using Ramipril ）. A week at least one measurement of blood pressure during the treatment,before treatment and 24 weeks after treatment for ambulatory blood pressure monitoring（OPB）. Results The combinative treatment decreased significantly blood pressure. The treatment group compared with the control group was significant （P〈0.05）,the second group after treatment and before treatment also have significant differences （P〈0.05）. Conclusions It is an effective way to treat age-related hypertensive patients with combination therapy with Ramipril and Amlodipine and individual use of Ramipril,but the combination therapy with Ramipril and Amlodipine is more effective with better tolerance.
出处
《中国实用医药》
2009年第6期88-90,共3页
China Practical Medicine
