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桑枝颗粒提取物对α-葡萄糖苷酶的抑制作用研究 被引量:12

Study on the function of α-glucosidase inhibitor from Ramulus Moki(Sangzhi)
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摘要 目的初步分离桑枝颗粒提取物中对α-葡萄糖苷酶的抑制活性成分。方法利用超滤工艺对桑枝颗粒提取物进行纯化。结果在同样的样品浓度下,桑枝颗粒提取物中相对分子量在5×105D~10×105D的组分的抑制活性最高,抑制率达68.0%。结论相对分子量在5×105D~10×105D的组分对α-葡萄糖苷酶的抑制活性最高。 Objective To determine the inhibition activity of α-glucosidase from Ramulus Moki( Sangzhi). Methods The extract of Ramulus Moki(Sangzhi) was separeted by ultra_filtration. Results On the same eoncertration condition, the extreatment of relative molecular weight between 5×105 D and 10 × 105 D has the biggest inhibition activity, the inhibitor rate was 68.0 percent. Conclusion The extreatment of relative molecular weight between 5 × 10s and 10 × 10s D has the biggest inhibition activity.
出处 《中国实用医药》 2009年第6期166-167,共2页 China Practical Medicine
关键词 桑枝 超滤 Α-葡萄糖苷酶 抑制活性 Ramulus Moki (Sangzhi) Ultrafiltration α-glucosidase Inhibition activity
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