摘要
药源性味觉障碍是指药物所致味觉丧失、味觉异常和味觉减退。目前有上百种药物可引起味觉障碍。抗感染药物、心血管药物、神经精神疾病用药、抗肿瘤药物是最常见的致味觉障碍药物。体内锌离子浓度降低可能是药源性味觉障碍的主要机制之一。药源性味觉障碍能影响患者的食欲、营养摄入、生活质量与情绪状况,尤其是用药依从性。因此,医师应关注临床发生的药源性味觉障碍。
The term of drug-induced taste disorders refers to agusia, dysgusia, and hypogusia due to drugs. More than one hundred drugs can cause taste disorders. The main drugs causing taste disorders are anti-infectives, cardiovascular drugs, drugs used in neuropsychopathy, and antineoplatics. One of the plausible mechanisms of drug-induced taste disorders is the reduction of zinc concentration in human body. Drug-induced taste disorders can negatively influence appitite, food intake, quality of life, emtional state, and importantly, medication compliance. Therefore, doctors should care for the drug-induced taste disorders occurring in clinical practice.
出处
《药物不良反应杂志》
2009年第3期191-195,共5页
Adverse Drug Reactions Journal
关键词
味觉障碍
药源性疾病
药物不良反应
预防
处理
taste disorders
drug-induced diseases
adverse drug reactions
prevention
treatment
