2型糖尿病肾病与中心性肥胖的相关研究

Relation between diabetic nephropathy in type 2 diabetic patients and central obesity

目的研究2型糖尿病肾病(DN)与中心性肥胖之间的关系。方法应用Logistic回归分析方法回顾性分析352例2型糖尿病患者的年龄、病程、血压、体重指数、腰臀比、空腹血糖、糖化血红蛋白、血脂等与糖尿病肾病间的相关性。结果糖尿病肾病(DN)组的病程、体重指数、腰臀比、三酰甘油、胆固醇、低密度脂蛋白、尿素氮、肌酐均明显高于糖尿病非肾病(DM)组;Logistic回归分析提示DN与病程、腰臀比、三酰甘油、胆固醇、低密度脂蛋白有相关性。结论减轻体质量,控制血脂、血压、血糖可在某种程度上延缓DN的发生与发展。

Objective To study the relation between diabetic nephropathy in type 2 diabetic patients and central obesity.Methods The relation was retrspective analysed with logistic regression between 352 type 2 diabetic patients ’age,duration of diabetes,blood pressure,body mass index,waist-to-hipratio,fasting plasma glucose,glycosylated HbA1c,blood lipid and diabetic nephropathy.Results Durationg of diabetes,body mass index,waist-to-hipratio,TG,TC,LDL-C,Urea nitrogen,Creatinine were higher in those in DN group than those in DM group.The logistic regression suggested the relation between diabetic nephropathy and durationg of diabetes,waist-to-hipratio,TG,TC,LDL-C.Conclusion To control body weight,blood lipid,blood pressure,serum glucose can delay the generation and development of diabetic nephropathy.