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焦虑症患者的多导联听觉P300事件相关电位研究

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摘要 目的研究焦虑症患者的16导听觉事件相关电位P300的局部脑区强度分布规律。方法用脑诱发电位仪记录焦虑症患者和正常人的16导事件相关电位(ERPs)P3a和P3b,分析受试者在额区、颞区、中央区和顶区等的P300幅度分布规律,研究焦虑症患者异常特征。结果焦虑症患者的P3a和P3b波幅的额区/顶区比值较正常对照组显著降低;颞区/顶区比值也显著降低;此外,P3a波幅的中央区/顶区比值显著增加。结论通过记录多导ERPs,并计算局部脑区的P300平均波幅,比对分析P300脑区强度分布,能揭示焦虑症患者的异常ERPs特征,有助于提高P300诊断焦虑症的特异性水平,
出处 《中华物理医学与康复杂志》 CAS CSCD 北大核心 2009年第7期488-490,共3页 Chinese Journal of Physical Medicine and Rehabilitation
基金 广东省自然科学基金资助项目(06028566)
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