T细胞急性淋巴细胞白血病中的染色体易位及其受累基因的研究进展
被引量：1
摘要
染色体易位在T细胞急性淋巴细胞白血病（T-ALL）中是非常普遍的现象。易位涉及的癌基因在T-ALL的发病机制中起重要作用。T-ALL染色体易位主要包括涉及T细胞受体（TCR）基因位点的染色体易位和形成融合基因的染色体易位。通过对染色体易位导致相关癌基因表达改变的研究来探讨T-ALL的发病机制，为发展临床上有效的相关特异性治疗提供可能。本文就T-ALL中染色体易位和涉及基因的研究进展作一综述。
出处
《国际输血及血液学杂志》
CAS
2009年第4期324-327,共4页
International Journal of Blood Transfusion and Hematology
基金
国家自然科学基金（30871091）
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