正常人眼前段组织与房角开放度数的关系

Relationship between Structure of Anterior Segment Tissue and Open Angle in Normal Subjects

【目的】分析正常人房角开放度数(AA)与眼前段结构的关系。【方法】收集211例(211只眼)正常人,采用眼前段光学相干断层扫描仪(AS-OCT)扫描其前房和晶状体,并测量前房深度(ACD)、前房横径(ACHD)、解剖前房深度(AACD)、睫状体带长度(CBL)、虹膜厚度(IT)、晶状体厚度(LT)、晶状体位置(LP)以及晶状体前极的位置(LAAP)。采用直线相关分析这8个参数与AA的关系。【结果】AA的均值为(40±17)°,男性(44±18)°,女性(37±16)°,比较差异有统计学意义(t=2.893,P=0.004)。AA与ACD(r=0.721,P=0.000)、LT(r=-0.545,P=0.000)、CBL(r=0.615,P=0.000)、LAAP(r=-0.717,P=0.000)、LP(r=0.557,P=0.000)和ACHD(r=0.175,P=0.011)相关,与AACD(r=0.130,P=0.059)、IT(r=0.129,P=0.061)无相关性。【结论】女性的房角比男性窄;在眼前段组织中,决定正常人房角宽窄的最关键的因素为晶状体、睫状体和虹膜根部的附着位置。

[Objective] To study the relationship between structure of anterior segment tissues and open angle（AA） in normal subjects. [Methods] A total of 211 eyes from 211 normal subjects were enrolled, whose anterior chambers and lens were scanned using anterior segment optical coherence tomography （AS-OCT）. The measuring items included AA, anterior chamber depth （ACD）, anterior chamber horizontal diameter （ACHD）, anatomical anterior chamber depth （AACD）, ciliary band length （CBL）, iris thickness （IT）, lens thickness （LT）, lens position （LP） and lens anterior apex position （LAAP）. The relationship between the 8 biometric parameters and AA was analyzed using linear correlation, respectively. [Results] The mean of AA was （40 ± 17）°, with （44 ± 18）° in male, and （37 ± 16）° in female. The difference of AA between male and female was statistically significant （t = 2.893, P = 0.004）. There was significant correlation between AA and ACD （r = 0.721, P = 0.000）, LT （r = -0.545, P = 0.000）, CBL （r = 0.615, P = 0.000）, LAAP （r = -0.717, P = 0.000）, LP （r = 0.557, P = 0.000）, and ACHD （r = 0.175, P = 0.011）. There was no significant correlation between AA and AACD （r = 0.130,P = 0.059）, IT （r = 0.129,P = 0.061）. [Conclusion] The AA of females was narrower than that of males. In normal subjects, the most important factors which determine AA are the lens, the location of the peripheral iris and ciliary body.