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干扰素联合普米克令舒吸入治疗毛细支气管炎的疗效

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摘要 目的探讨干扰素联合普米克令舒雾化吸入治疗毛细支气管炎的疗效。方法126例毛细支气管炎患儿随机分为2组:对照组(64例)与治疗组(62例)。对照组采用抗感染、舒张支气管、止咳、镇静等治疗。治疗组在对照组治疗基础上加用重组人干扰素-α2b注射液5万U/kg肌注,1次/d,共3 d;普米克令舒0.5 mL用生理盐水稀释至2 mL,放入带空气压缩泵的雾化吸入器内雾化吸入,2次/d,共7 d。结果治疗组显效、有效、无效例数分别为48、10、4例,有效率为93.5%;对照组显效、有效、无效例数分别为25、22、17例,有效率为73.4%。2组有效率比较差异有显著性(P<0.01)。2组患儿气促、咳嗽、肺部啰音消失的平均时间比较,治疗组明显短于对照组,均P<0.01。结论干扰素联合普米克令舒雾化吸入治疗毛细支气管炎疗效较好,并可缩短病程,进而可以避免或减轻全身使用激素的不良反应。
出处 《实用临床医学(江西)》 CAS 2009年第6期80-81,共2页 Practical Clinical Medicine
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