高压氧治疗下小儿视网膜变化的临床研究

CLINICAL STUDY OF RETINA CHANGE IN CHILDREN WITH HYPERBARIC OXYGEN THERAPY

目的观察临床高压氧治疗下小儿视网膜的变化,评价高压氧疗法在儿科领域应用的安全性及对视网膜可能产生的毒副作用。方法选择2003年1月—2006年6月我科行高压氧治疗的小儿(含足月产正常体重儿、婴儿、幼儿及儿童)100例,在不同治疗压力、次数、氧浓度下进行高压氧治疗,在此期间及疗程结束后6个月内连续进行眼底检查观察其视网膜的变化。结果全部患儿在高压氧治疗期间及治疗结束后6个月内经眼底检查未发现视网膜病变。结论只要严格遵循高压氧治疗操作的常规,高压氧在临床儿科疾病上的应用是安全的,并不会产生视网膜病变。

Objective To observe retina change of the child with hyperbaric oxygen therapy （HBOT） and evaluate the safety and possible side effect of HBOT on child. Methods In our department, 100 children （including full- term normal weight neonate, infant, toddler, preschooler and schoolchild） who received HBOT of different pressure, times and oxygen concentration according to their diseases were observed from Jan 2003 to June 2006. Their eyeground were continuously examined during the course and the 6 months after the treatment. Results Retinopathy was not detected dur- ing the eouree and the later 6 months after the treatment. Conclusion It is safe to use HBOT in pediatrics if the rules of HBOT are followed strictly. With the condition of clinical treatment, HBOT could not bring retinopathy.