针刺“内关”穴对快速性心律失常大鼠心肌细胞cAMP含量的影响

Acupuncture ＂Nei guan＂ Point for Tachyarrhythmia Myocardial cAMP Content of Cells

[目的]通过研究快速性心律失常大鼠心肌细胞中cAMP含量的变化，揭示快速性心律失常的发病机理，阐述针刺“内关”穴的调节作用机制。[方法]以舌下静脉注射0．002％的乌头碱（1mL／kg）复制快速性心律失常大鼠模型，用电针“内关”穴对实验大鼠治疗，以模型空白组和电针非经非穴为对照组，用放射免疫法测定cAMP含量。[结果]模型组与正常组相比cAMP含量明显升高，“内关”穴组与模型组相比cAMP含量明显降低。[结论]快速性心律失常与心肌细胞中cAMP含量有关；针刺“内关”穴通过调节大鼠心肌细胞中cAMP含量起到一定的治疗作用。

[ Objective] through research Tachyarrhythmia myocardial cAMP content of cells changes, revealing Tachyarrhythmia pathogenesis,the needle ＂Nei guan＂ point adjustment mechanism. [ Methods ] sublingual intravenous injection of 0.002% aconitine （1 mL/kg） copy of Tachyarrhythmia rat model, electric needle ＂Nei guan＂ point for the treatment of experimental rats in order to model electro -acupuncture group and the blank of non - by the non -points for the control group,measured by radioimmunoassay cAMP content. [ Results] model group compared with the normal group was significantly increased cAMP content,＂ Nei guan＂ point group and model group were significantly lower compared to cAMP. [ Conclusion ] Tachyarrhythmias in myocardial cells and cAMP content; acupuncture ＂Nei guan＂ point in rats by regulating cAMP content in cardiac myeeytes play a role in the treatment.