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维生素B_6及抗Hp治疗对急性冠状动脉综合征预后及血炎症介质的影响 被引量:3

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摘要 目的探讨维生素B6及抗幽门螺旋杆菌(Hp)治疗对急性冠状动脉综合征(ACS)患者再发冠心病事件及血炎症介质的影响。方法将伴Hp感染的ACS患者随机分为三组,对照组采用常规药物治疗,治疗A组加用奥美拉唑、克拉霉素和阿莫西林,治疗B组在治疗A组基础上加用维生素B6。疗程均为10 d。观察再发冠心病事件的发生率,检测血Hp IgG、超敏C反应蛋白(hsCRP)和IL-6。结果随访12个月,对照组、治疗A组、治疗B组再发冠心病事件的发生率分别为27.9%、15.7%、11.94%。治疗A组和B组Hp IgG、hsCRP及IL-6水平显著降低,治疗B组更明显。结论维生素B6及抗Hp治疗可降低冠心病事件的发生率,降低血炎症介质水平。
出处 《山东医药》 CAS 北大核心 2009年第28期83-84,共2页 Shandong Medical Journal
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