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国产氯吡格雷对冠心病患者阿司匹林抵抗影响的临床研究

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摘要 目的观察国产氯吡格雷(泰嘉)对冠心病患者阿司匹林抵抗(AR)的影响。方法采用全血电阻法监测冠状动脉造影和(或)64层冠脉CT证实的冠心病患者178例和51例对照者的血小板聚集率(PAG),冠心病患者经氯吡格雷75mg/d,治疗一周后再次测定冠心病患者的PAG,比较加用氯吡格雷前后PAG的变化。结果冠心病患者中49例(28%)出现AR,使用国产氯吡格雷治疗一周后,PAG明显下降。结论冠心病患者中AR的发生率升高,加用氯吡格雷治疗可减少AR的发生。
机构地区 山西省人民医院
出处 《中西医结合心脑血管病杂志》 2009年第7期773-775,共3页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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