泮托拉唑与奥美拉唑治疗消化性溃疡合并出血的效果比较

Effect of Pantoprazole and Omeprazole Treatment Peptic Ulcer Bleeding Merger

目的比较泮托拉唑与奥美拉唑治疗消化性溃疡合并出血的临床效果。方法将经纤维胃镜检查确诊为消化性溃疡104例,随机分为泮托拉唑组(观察组)与奥美拉唑组(对照组)各52例。在基础治疗上观察组给予泮托拉唑,对照组给予奥美拉唑,观察两组的疗效和不良反应。结果治疗(2～6)天后,两组患者的呕血和黑便次数与第1天相比差别有显著性(P<0.05),而两组治疗效果比较无显著性差别(P>0.05)。结论泮托拉唑与奥美拉唑治疗消化性溃疡并出血的临床疗效相当,两者起效快,不良反应少,两药相比具有同样的有效性和安全性。

Abstract： Objective To compare the clinical effects of Pantoprazole and 0meprazole in the treatment of Peptic ulcer bleeding . Methods 104 Patients of peptic ulcer Confirmed by Fiberoptic gastroscopy were randomly divided into pantoprazole group （observation group） and Omeprazole group （control group） 52 cases each.The basis of observation in the treatment of pantoprazole given the observation group, omeprazale given the control group, the two groups were observed efficacy and adverse reactions. Results The treatment of （2 - 6） days later, two groups of patients with hematemesis and melena number 1 days compared with significant difference （P 〈0.05）, and Comparison of therapeutic effects were no significant differences （P〉 0.05） .Conclusion Pantoprazole and Omeprazole in the Treatment of peptic ulcer bleeding considerable clinical efficacy, both of rapid onset, fewer adverse reactions, compared to the two drugs have the same efficacy and safety.