2008年大学新生乙肝病毒感染状况的调查分析

Study and analysis on situation of hepatitis B virus infection in new enrollment of college students in 2008

目的了解新入学大学生乙型肝炎病毒(HBV)感染状况,为我校的预防保健提供依据。方法对2008级全体新生进行肝功能及乙肝两对半测定。结果本校2008级新生的乙型肝炎病毒表面抗原(HBsAg)阳性感染率为5.5%,低于社会人群的感染率,但男女之间有差异,男性感染率高于女性感染率;HBV感染模式均以小三阳[HBsAg、乙型肝炎病毒e抗体(HBeAb)、乙型肝炎病毒核心抗体(HBcAb)阳性]和大三阳[HBsAg、乙型肝炎病毒e抗原(HBeAg)、HBcAb)居多,HBsAg阳性中丙氨酸氨基转移酶(ALT)升高者大多存在于小三阳的人群中。结论为了很好地控制传染病的流行,加强乙肝疫苗注射,对大中小学生从入学开始进行加强防病知识的宣传教育是很有必要的。

Objective To understand the situation of hepatitis B virus infection in new enrollment of college students for the basis of preventive health - earing in this university. Methods Determination of liver function and 5 items of HBV markers was carried out in all new students entering into school in 2008. Results The positive rate of HBsAg in new students was 5.5%. The rate of infection was lower than that of social population. But there was difference between men and women, and men have a higher infection rate than that of women. The modes of hepatitis B virus infection were the small three positives （HBsAg, HBeAb and HBcAb） and the large three positives （HBsAg, HBeAg and HBeAb）, Mostly elevated level of ALT was seen in population with positive HBsAg, HBeAg and HBeAb. Conclusion In order to effectively control infectious diseases, it should be put emphasis on strengthening the vaccination of B hepatitis virus vaccine. It is necessary to strengthen the health education on disease prevention .