20例多发性硬化的MRI诊断分析

To Analyze the Diagnosis of 20 Patients with Multiple Sclerosis

目的:探讨多发性硬化的MRI表现。方法:回顾分析多发性硬化患者20例,结合文献,分析其头颅、脊髓MRI表现。结果:所有患者脑或脊髓平扫均发现病灶,主要发生在双侧脑室周围白质区或颈段脊髓。双侧脑室周围病灶表现为多发大小、形态不一的斑片状等长T1、长T2异常信号,病灶长轴多与脑室壁垂直排列。脊髓病灶表现为纵行长条状等长T1、长T2异常信号。静脉注射Gd-DTPA后活动性病灶呈斑片状、斑点状或边缘强化。经激素治疗病变范围缩小或恢复正常,强化程度减弱或无强化。结论:结合临床资料,MRI对多发性硬化的诊断有重要意义。

Objective： To investigate the MRI findings of multiple sclerosis（MS）. Methods： Retrospectively analyze the MRI findings in 20 patients with MS, in combined with, to analyze the MRI findings of brains or spinal cords . Results： In plain scan the lesions were detected in brains or spinal cords, Most lesions were located in white matter around lateral ventricle and cervical cord. the lesions around lateral ventricle showed abnormal signal with different size and shape, the signal were manifested as patches shape with high singal change on T2WI and low- or iso- signal on T1WI;long axial of the lesions and lateral ventricle were usually vertical. The string lesions of spinal cords which parallel spine cord long axial; the lesions showed low - or iso- signal intensity on T1WI and high - signal intensity on T2WI, showing patchy or marginal or mottled enhancement after intravenously administration of Gd - DTPA. After the patient was treated with standard hormonotherapy, the size of the lesions became small or returned normal with weakened, or without, enhancement. Conclusion： Combined with clinical histories, MRI has important sense in the diagnosis of MS.