摘要
目的探讨颈动脉粥样硬化(CAS)与脑梗死患者认知障碍、卒中特异性生存质量的关系。方法将符合研究标准的首发脑梗死患者根据颈动脉超声情况分为轻中度CAS组和重度CAS组。运用简易智力状态试验(MMSE)、脑卒中影响量表(SIS)3.0版进行评定。结果重度CAS患者MMSE注意力/计算力、语言理解和总分,SIS行动能力和手功能维度评分均低于轻中度CAS组(P<0.05)。结论颈动脉粥样硬化程度对脑梗死患者认知功能和生存质量均有负面影响。
Objective To investigate the relationship between carotid atherosclerosis （CAS） and cognitive impairment, stroke- specific quality of life of patients with cerebral infarction. Methods Patients enrolled were divided into mild-to-moderate CAS group and severe CAS group after carotid ultrasound. They were assessed with Mini Mental State Examination （MMSE） and Stroke Impact Scale （SIS） Version 3.0. Results The scores of attention/calculation, comprehension, and total of MMSE, the mobile ability and hand function dimensions of SIS were all lower in severe CAS group than in mild-to-moderate CAS group （P〈0. 05）. Conclusion Carotid atherosclerosis may further impair the cognitive function and quality of life of cerebral infarction patients.
出处
《中国康复理论与实践》
CSCD
2009年第7期652-653,共2页
Chinese Journal of Rehabilitation Theory and Practice
基金
北京市中医药科技项目(JJ-2008-020)
北京市中医药管理局重点学科资助项目(京中重VI26)
关键词
颈动脉粥样硬化
脑梗死
认知障碍
生存质量
carotid atherosclerosis （CAS）
cerebral infarction
cognitive impairment
quality of life
