摘要
目的优化便塞通颗粒水提澄清工艺。方法采用水提液絮凝澄清法与离心法平行对比,以辛弗林、总黄酮保留率及干膏率为评价指标优选水提液澄清工艺。结果高速离心澄清工艺能有效保留辛弗林及总黄酮等有效成分。选取最佳纯化条件为:药液浓缩至相对密度为1.05(60℃),以12000r.min-1高速离心10min。结论该法简单可取,适合于便塞通颗粒水提澄清工艺。
Objective To optimize the removing impurity method from water of Bian Setong Granules. Methods The methods of clarifying water of Bian Setong Granules by clarificant and by centrifuging were compared with the remaining rates of Synephrine, total flavonoids and dried extract as indexes. Results Centrifuging could remain effective active components. The most optimal clarifying condition was to concentrate the mixture to relative density of 1.05 (60℃) , and centrifuge in 12 000 r/min - 1 for 10 minutes. Conclusion The process is simple and preferable and can be used to clarify Bian Setong Granules.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2009年第7期1686-1688,共3页
Lishizhen Medicine and Materia Medica Research
基金
四川省教育厅科研基金资助(No.2003A068)
关键词
水提液
澄清
离心法
絮凝澄清法
Water - extraction
Clarifying
Centrifuging
Natural clarify medium