摘要
目的筛选藏药涤痰平喘胶囊制剂提取工艺。方法以浸膏得率和淫羊藿苷的含量为指标,采用L9(34)正交设计法筛选最佳提取工艺。结果制备工艺影响因素依次为:煎煮时间(A)>煎煮次数(B)>加水量(C),最佳制备工艺条件为A1B3C1,即去油达玛(陇蜀杜鹃)药渣和处方量的皂荚、淫羊藿等加8倍量水,提取3次,每次40min。结论筛选的制剂工艺合理,质量稳定可靠;淫羊藿苷含量测定为该制剂质量控制提供依据。
Objective To screen of aqueous extraction process of Ditanpingchuan capsule in Tibetan medicine method using the yield of extractum and the content of icariin as indexes, the optimum extraction conditions of Ditanpingchuan capsule was studied with the orthogonal test L9 （ 3^4 ）. Results The influencing power of factor was described as ： A 〉 B 〉 C （ A ： decoction times, B ： decoction frequency, C： added water volume）. The optimum preparation conditions were A1B3 C1 , i.e. drugs of a decoction of Rhodo- dendron przewalskii Maxim without volatility oil and Gleditsia, Icariin, 8 times volume of water, decoction for 3 times and 40 minutes every time. Conclusion The optimum extraction procedures are rational ,feasible, and provide foundation for production.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2009年第7期1693-1694,共2页
Lishizhen Medicine and Materia Medica Research
基金
青海省科技厅重点科技攻关项目(No.2007-N-134)
