氩氦刀靶向消融治疗实体肿瘤的评价

Evaluation of targeted argon-helium cryoablation in treating solid tumors

氩氦刀靶向消融治疗已广泛应用于肿瘤治疗,其基本原理是超低温(<-140℃)作用于病变组织引起细胞内外冰晶形成、细胞破裂,从而引起一系列物理化学变化,导致肿瘤组织细胞坏死。本文介绍了氩氦刀靶向消融治疗的引导方式、冷冻范围与冷冻时间、冷冻免疫、疗效评价与联合治疗等问题。

Argon-helium cryosurgical system has been widely used in the treatment of solid tumors. The basic mechanism of this technique is that the ultra low temperature （below 140℃ ） can act on the diseased tissues, resulting in the formation of ice crystals both inside and outside of the cells and causing the rupture of the cells, which will further produce a series of physical and chemical changes and finally bring about the necrosis of tumor cells. This paper aims to introduce the argon-helium cryosurgical system, focusing on its guiding mode, freezing extent and time, freezing immunity, curative effect and combination of treatments.