肿瘤冷冻消融器械的发展现状

The current situation of the development of cryoablation apparatus

本文综合介绍了冷冻消融的发展历程、机制、优劣势、应用范围,以及目前世界上最先进的肿瘤治疗产品及其原理和性能,如加拿大CryoCath公司用于消融肺静脉口的ArcticFront球囊导管、美国Endocare公司的通过调节滑钮位置即可产生5种不同直径冰球的V-probe探针、以色列Galil-medical公司的1.47mm直径探针、丹麦Metrum-cryoflex公司的Cryo-s系列冷刀、刘静研究组的冷热刀和"纳米冷冻"技术,并对冷冻消融将来的发展方向提出自己的见解。

This article aims to introduce the progress, mechanism, advantage, disadvantage and application of cryoablation technique, as well as the most advanced instruments in the world nowadays, which have been clinically used for the treatment of cancer, and their operating principles and functions. The following are some of the state-of-the-art cryoablation instruments： the ArcticFront balloon catheter for the ablation of pulmonary, vein （CryoCath Technologies Inc., Canada）, the V-probe （Endocare Inc., U.S.A.）, which can generate iceball of five different diameters by adjusting the slip-twisting position, the 1.47 mm diameter probe （Galil-medieal Inc., Israel）, the Cryo-s （Metrum-eryoflex Inc., Denmark）, and cryosurgery- hyperthermia equipment and ＂nano frozen＂ technique （Liu Jing＇s Study Group）. The prospect of cryoablation technique is also discussed in this paper.