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CD62P和CD63评价羟乙基淀粉130/0.4对血小板活化抑制的意义 被引量：2

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摘要 目的探讨CD62P和CD63在羟乙基淀粉(HES)130/0.4对血小板(PLT)活化抑制的意义。方法采用流式细胞术检测输HES130/0.4前基础值(T1期)、输注完后(T2期)、手术完毕1h(T3期)的PLT膜糖蛋白CD62P、CD63的表达水平。结果CD62P、CD63表达水平在T2期平均分别下降了24.3%和24.0%,明显低于T1期,差异有统计学意义(P<0.01);CD62P在术后1 h恢复至T1期水平(P>0.05)。CD63表达水平在术后1 h仍有6.7%(2/30)的病例未达到正常水平(P<0.05)。结论作为HES130/0.4对PLT活化抑制的评价中,以CD62P和CD63两者联合检测为宜。
作者 骆华 骆方军
机构地区 浙江省诸暨市人民医院检验科
出处 《检验医学》 CAS 北大核心 2009年第7期542-544,共3页 Laboratory Medicine
关键词 血小板膜糖蛋白 CD62P CD63 羟乙基淀粉130/0.4
分类号 R446.11 [医药卫生—诊断学]
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共引文献23

同被引文献16

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检验医学
2009年 第7期

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