介入治疗肝血管瘤的临床研究

The clinic study of patients with liver cavernous hemangioma treated with Pingyangmycin lipiodol emulsion

目的:探讨平阳霉素碘油乳剂超选择栓塞治疗肝血管瘤的临床疗效和治疗体会。方法:对23例肝血管瘤患者,采用平阳霉素碘油乳剂超选择性动脉插管行栓塞治疗,观察治疗前和治疗后6个月、12个月时患者临床症状、肿瘤大小的变化以及出现的并发症。结果:所有患者在术后6个月和12个月复查CT,见瘤体血供消失,其内碘油沉积良好,并出现瘤体缩小、碘化油聚积征象。术前血管瘤直径为(8.1±2.2)cm,术后6个月血管瘤直径为(5.4±1.3)cm,术后12个月血管瘤直径为(3.4±1.2)cm。治疗前有临床症状者治疗后缓解或消失。术后均未出现胆囊坏死、胆管狭窄和肝坏死等严重并发症发生。结论:超选择性肝动脉插管平阳霉素碘油乳剂栓塞治疗巨大肝血管瘤是一种疗效肯定、相对安全较为理想的治疗方法。

Objective： To evaluate safety and efficacy of superselectively hepatic artery embolization treatment with Pingyangmycin lipiodol emulsion for patients wida liver eavemous hemangioma. Methods：23 patients with hepatic eavemous hemangioma underwent superselectively hepatic artery enabolization with Pingyangmycin lipiodol emulsion. The changes of clinic symptoms, tumour diameters, and complications were observed before treatment and at 6 months and, at 12 months after treatment.Results：CT scans showed that the supplication of blood disappeared, and tumor diameter reduced in all patients at 6 months and 12 months after treatment. The lipiodol deposited well in the tumoral lesions of most patients. The mean tumor diameter was 8.01 ± 2.2 cm before intervention, 5.4 ±1.3 cm at 6 months after treatment, and 3.4 ± 1.2 cm at 12 months after treatment. The clinic symptoms alleviate or disappear in all patients. No severe complications such as gallbladder injury, bile stuct strick, and liver function failure developed during and after therapy. Condusion：Superselectively hepatic artery embolization treatment with Pingyangmycin lipiodol emulsion is an effeetve and safe method for patients with hepatic cavernous hemangioma.