慢性胃炎患者红细胞免疫功能的变化

Alteration of erythrocyte immune function in patients with chronic gastritis

目的探讨慢性胃炎(CG)患者红细胞免疫功能的变化。方法对88例慢性胃炎患者进行红细胞免疫功能检测。结果萎缩性胃炎患者红细胞C_(3b)受体花环率(RBC-C_(3b)RR)、免疫粘附促进因子(RFER)明显低于对照组(P<0.05),免疫复合物花环率(RBC-ICR)、免疫粘附抑制因子(RFIR)明显高于对照组(P<0.05);而浅表性胃炎患者RBC-C_(3b)RR、RBC-ICR、RFER、RFIR与对照组比较差异无统计学意义(P>0.05)。结论检测慢性胃炎患者红细胞的免疫功能对于鉴别诊断和评估愈后具有十分重要的临床意义。

Objective To investigate the （RBC） in patients with chronic gastritis. Methods change of immunologic function of red blood cell The immunologic function of RBC in 88 cases of chronic gastritis was dynamically detected with yeast rosette method. Results The results showed that RBC-C3b receptor rosette （RBC-C3b-RR） rate and RBC immune adherence enhance factor （RFER） rate were significantly lower （P〈0.05） and RBC immune complex rosette （RBC-ICR） rate and RBC im- mune adherence inhibitor factor （RFIR） were significantly higher （P〈0.05） in the patients with a- trophic gastritis than those in control group. In the patients with superficial gastritis, the difference had no distinct significance （P〉0.05）. Conclusion The immunologic function of red blood cell （RBC） measurement plays an important role in differential diagnosis and prognosis evaluation of chronic gastritis.