不同项群优秀运动员细胞体液免疫机能状态的评定

Evaluation of immune function of athletes engaged in different athletics

目的研究中国优秀运动员的基础免疫状态参数,为了解运动员的免疫功能状态、及时调整运动负荷、指导训练及采取一些合理的恢复措施提供依据。方法对从事不同运动项目运动员的T、B、NK淋巴细胞亚群等免疫参数进行测定,按运动项目分组,分别与正常对照组比较。结果运动员组CD3+、CD3+CD4+、CD3+CD8+、CD3-CD19+和CD3-CD56+均较正常对照组低(P<0.01),而CD4/CD8无统计学差异。B组(技能主导类项群)、C组(综合性项群)CD3+、CD3+CD4+均高于A组(体能主导类项群)(P<0.01);C组CD3-CD56+低于A组(P<0.01);A组、C组CD3-CD19+均低于B组(P<0.01)。结论运动员T、B、NK淋巴细胞基础免疫参数均较正常人低;不同项群运动员其免疫指标不同。

Objective To evaluate the basic immune parameters of Chinese excellent athletes in order to provide effective training information. Methods Percentages of T, B, and NK cell subpopulations from peripheral blood of athletes engaged in different athletics were detected by flow cytometry. The athletes were divided into different groups according to different athletics and compared with controls. Results The percentages of CD3^＋ , CD3^＋ CD4^＋ , CD3^＋ CD8^＋ , CD3^-CD19^＋ and CD3^-CD56 ^＋ cells in athletes were lower than those in controls（P 〈0.01 ）. There was no difference in value of CD4/CD8 between the two groups. The percentages of CD3^＋ and CD3 ^＋ CD4^＋ T lymphocytes in groups B and C were significantly higher than those in group A（ skill event group） （ P 〈 0.01 ）. The percentage of CD3^-CD19 ^＋ lymphocytes in groups A and C was lower than that in group B （ P 〈 0.01 ）. The percentage of CD3^-CD56^ ＋ lymphocytes in group C was lower than that in group A （ P 〈 0.01 ）. Conclusion Immune parameters are significantly lower in Chinese excellent athletes than in healthy persons, and are different in athletes engaged in different athletics.