妊娠高血压疾病血液流变学指标分析

Analysis of the Hemorheology Indexes of Patients with Pregnancy-induced Hypertension

目的探讨妊娠高血压疾病（PIH）患者的血液流变学指标变化。方法对48例PIH患者组、30例正常妊娠对照组和30例正常未孕妇女的血液流变学及部分生化指标进行分析研究。结果相对于正常妊娠组，PIH患者呈高粘滞血症伊〈0．01），胆固醇、甘油三酯及纤维蛋白原也有显著增高（P〈0．01）红细胞压积、红细胞聚集和刚性指数有不同程度升高（P〈0．05），而红细胞变形和电泳指数有明显降低（P〈0．05）。结论该结果证实了PIH病理过程中存在着血液流变学异常及微循环障碍。

Objective To investigate the disease in patients with pregnancy-induced hypertension hemorheology changes.Methods Hemorheology results and some biochemical indexes of 48 cases of patients with pregnancy induced hypertension group, 30 cases of normal pregnancy group and 30 cases of normal non-pregnant group were analysed.Results Compared with the normal pregnancy group, pregnancy-induced hypertension syndrome was hyperviscosity syndrome （P〈0.01）,cholesterol,triglycerides and fibrinogen also significantly increased （P〈0.01）; erythrocyte sedimentation rate,erythrocyte aggregation index and the rigidity index increased to different extents （P 〈0.05）,and erythrocyte deformability and electrophoretic index decreased significantly （P〈0.05）.Conclnsion The results confirm there are abnormal hemorrheology and microcirculation in the pathological process of the pregnancyinduced hypertension disease.