舒芬太尼复合氯诺昔康在老年人胸部手术后静脉自控镇痛的应用

Application of sufentanil combined with lornoxicam in the elderly patients controlled intravenous analgesia after thoraces surgery

目的观察舒芬太尼复合氯诺昔康在老年人胸部手术后静脉自控镇痛的应用效果。方法60例老年人普胸手术后行静脉自控镇痛,随机分为两组:A组(舒芬太尼1μg/ml加入0.9%生理盐水稀释到100ml,PCIA)。B组(舒芬太尼0.5μg/ml联合氯诺昔康0.32mg/ml加入0.9%生理盐水稀释到100ml,PCIA)。观察术后4、8、16、24、48h的镇痛效果、镇静评分及不良反应。结果两组镇痛效果比较差异无统计学意义(P>0.05)。镇静效果:A组镇静较强,与B组比较差异有统计学意义(P<0.05)。不良反应:两组恶心、呕吐、皮肤瘙痒发生率无统计学意义(P>0.05),两组均无呼吸抑制及胃出血发生。结论老年人普胸手术后行舒芬太尼复合氯诺昔康静脉自控镇痛效果好,不良反应少。

Objective To observe the effects of sufentanil combined with lomoxicam in the elderly patients controlled intravenous analgesia （PCIA） after thoraces surgery. Methods Sixty elderly patients scheduled for the thoraces sugery were divided randomly into two groups：sufentanil 1ug/ml in A group（ n = 30） and sufentanil 0. 5 μg/ml plus lornoxieam 0. 32 mg/ml in B group （n =30）. Each drug was diluted to 100 ml and infused by an pump at a rate of 2 ml/h. The sedative scores, visual analogue scales, and side effects were recorded at 4,8,16,24,48 hour after operation. Results There were no significant differences in the potency of analgesia between the two groups. The sedative scores of group A was more obviously than group B. The incidence rate of the side effects was same in group A and B, such as nausea, vomiting, swirl, and itch of skin. There were no respiratory depression and gastrorrhagia in the two goups. Conclusion PCIA with sufentanil combined with lomoxicam was safe and effective for the elderly patients after thoraces surgery.