乳癖散结胶囊联合舒肝理气丸治疗乳腺囊性增生病临床疗效观察

Objective of Rupisanjiejaonang add Shuganliqiwan in teatment mastopathy

目的观察乳癖散结胶囊联合舒肝理气丸治疗乳腺囊性增生病临床疗效。方法将396例乳腺囊性增生病患者随机分成三组:乳癖散结胶囊组、舒肝理气丸组和联合用药组,分别给于药物治疗。乳癖散结胶囊组单用乳癖散结胶囊4粒,口服,3次/d;舒肝理气丸组单用舒肝理气丸6g,口服,3次/d;联合用药组用乳癖散结胶囊4粒,口服,3次/d;同时服用舒肝理气丸6g,口服,3次/d。全程治疗观察时间为45d。结果乳癖散结胶囊组、舒肝理气丸组和联合用药组治疗有效率分别为63.6%(82/129),48.5%(64/132),83.7%(113/135)。乳癖散结胶囊组较舒肝理气丸组,有显著性差异(P<0.05);联合用药组对乳腺囊性增生病的治疗有效率均较单独服用乳癖散结胶囊组及单独服用舒肝理气丸组高,有非常显著性差异(P<0.01)。结论乳癖散结胶囊和舒肝理气丸联合用药对治疗乳腺囊性增生病效果明显优于单独用药。

Objective To appraise the effectiveness of Rupisanjiejiaonang add shuganliqiwan in treatment of mastopathy. Methods 396 case patiens undergoing mastopathy were randomly divided into 3 groups ： Rupisanjiejiaonang group （ reeived Rupisanjiejiaonang 4 capsule, oral, qid）, shuganliqiwan group （ recived Shuganliqiwan 6 g, oral, qid） and Rupisanjiejiaonang add Shuganliqiwan group（ recived Rupisanjiejiaonang 4 capsule,oral, qid and Shuganliqiwan 6 g, oral, qid）. All patiens experienced observation cf 45 days. Results The rate of effectivity were 63.6% （ 82/129, Rupisanjiejiaonang group ）, 48.5% （ 64/132 Shuganliqiwan group ）, 83.7% （113/135, Rupisanjiejiaonang add Shuganliqiwan group）. Compareing Rupisanjiejiaonang group with Shuganliqiwan group, the rate of effectiveness were increased significantly （ P 〈 0. 05 ） ; rate of Rupisanjiejiaohang add Shuganliqiwan group were increased significantly of three group （P 〈 0. 01 ）. Conclusion Rupisanjiejiaonang add Shuganliqiwan group were efficient in teating mastopathy.