摘要
脂蛋白相关磷脂酶A2（lipoprotein-associated phospholipase A2，Lp-PLA2）是心血管疾病的一种新型生物学标志物。它在有症状颈动脉粥样硬化斑块中的表达高于无症状颈动脉粥样硬化斑块，其产物溶血磷脂胆碱与组织氧化应激和炎症有关。另外，Lp—PLA2在颈动脉粥样硬化斑块的不稳定性差异中起着较为独特的作用。
Lipoprotein-associated phospholipase A2 （Lp-PLA2） is a novel biomarker for cardiovascular disease. Its expression in symptomatic carotid plaques is higher than that in asymptomatic ones, and its product lysophosphatidylcholine is associated with tissue oxidative stress and inflammation. In addition, Lp-PLA2 plays a more unique role in the unstable difference of carotid atherosclerotic plaques.
出处
《国际脑血管病杂志》
北大核心
2009年第6期459-462,共4页
International Journal of Cerebrovascular Diseases
