摘要
目的探讨米氮平对老年抑郁症的疗效和安全性。方法将62例抑郁症患者随机分为两组,分别予米氮平与马普替林治疗,疗程6周。于治疗前和治疗后1、2、4、6周末分别用汉密尔顿抑郁量表(HAMD)和副反应量表(TESS)评定疗效及不良反应。结果米氮平组显效率为76.7%,马普替林组为75.9%,两组比较差异无显著性(P>0.05),但米氮平起效快,不良反应轻微。结论米氮平与马普替林治疗老年抑郁症疗效相当,但米氮平起效快,不良反应少,安全性高。
Objective To study the clinical effects and safety of Mirtazapine in the treatment of the aged depression. Methods 62 aged depression victims are divide into two groups and are treated by using mirtazapine and Maputilin respectively. The course of treatment is 6 weeks. Hamilton Depression Scale （HAMD） and Treatment Emergent Symptom Scale（TESS） were used to test the treatment effects and side effects on the first, second, fourth and sixth week. Results The clinical effect of Mirtazapine group is 76. 7%, while that of Maputilin group is 75.9%. The clinical effect of Mirtazapine is similiar to Maputilin. But Mirtazapine has a quick effect and no side effeds. Conclusion The clinical effect of Mirtazapine is similiar to MaPutilin, but Mirtazapine has quick effect, less side effects and higher safety.
出处
《中国健康心理学杂志》
2009年第6期652-653,共2页
China Journal of Health Psychology
