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慢性淋巴细胞性白血病诊断和治疗进展 被引量：3

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摘要 慢性淋巴细胞性白血病(chronic lymphocytic <正>leukemia,CLL)是一种因细胞凋亡受阻而导致的B细胞恶性克隆增殖性疾病,表现为成熟的小淋巴细胞在外周血。
作者 余栋 赵维莅
机构地区 上海交通大学医学院附属瑞金医院血液科上海血液学研究所医学基因组学国家重点实验室
出处 《内科理论与实践》 2009年第4期341-345,共5页 Journal of Internal Medicine Concepts & Practice
基金 国家高技术研究发展计划(863 2006AA02A301) 国家自然科学基金(项目编号:30750335) 教育部新世纪优秀人才支持计划(项目编号:NCET-07-0556) 上海市科委国际合作项目(项目编号:08410708800) 霍英东青年教师基金(项目编号:111035)
关键词 慢性淋巴细胞性白血病 诊断 恶性克隆增殖性疾病 治疗 中位年龄 小淋巴细胞 细胞凋亡 淋巴组织
分类号 R733.72 [医药卫生—肿瘤] R457.7 [医药卫生—治疗学]
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参考文献10

  • 1Montillo M,Hamblin T,Hallek M,et al.Chronic lympho-cytic leukemia:novel prognostic factors and their rele-vance for risk-adapted therapeutic strategies[].Haematologica.2005
  • 2Rossi D,Zucchetto A,Rossi FM,et al.CD49d expression is an independent risk factor of progressive disease in early stage chronic lymphocytic leukemia[].Haemato-logica.2008
  • 3van Bockstaele F,Pede V,Janssens A,et al.Lipoprotein lipase mRNA expression in whole blood is a prognostic marker in B cell chronic lymphocytic leukemia[].Clinical Chemistry.2007
  • 4van Bockstaele F,Verhasselt B,PhilippéJ.Prognostic markers in chronic lymphocytic leukemia:a comprehen-sive review[].Blood Reviews.2009
  • 5O‘Brien S.New Agents in the Treatment of CLL[].Hematology Am Soc Hematol Educ Program.2008
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  • 7Sorror ML,Storer BE,Sandmaier BM,et al.Five-year follow-up of patients with advanced chronic lymphocytic leukemia treated with allogeneic hematopoietic cell transplantation after nonmyeloablative conditioning[].Journal of Clinical Oncology.2008
  • 8Sayala HA,Rawstron AC,Hillmen P.Minimal residual disease assessment in chronic lymphocytic leukaemia[].Bailliere s Best Practice and Research Clinical Haematology.2007
  • 9Watson L,,Wyld P,Catovsky D.Disease burden of chro-nic lymphocytic leukaemia within the European Union[].European Journal of Haematology.2008
  • 10Catovsky D,Ralfkiaer E,Muüller-Hermelink HK,et al.World Health Organization classification of tumours:pathology and genetics of head and neck tumours[].World Health Organization Classification of Tumours.2001

同被引文献13

  • 1Yee K W, O'Brien S M. Chronic lymphocytic leukemia: diagnosis and treatment [ J ]. Mayo Clin Proc, 2006,81 (8) : 1105-1129.
  • 2Cobert J, Hochberg E P, Abramson J S, et al. Nervous System Invasion occurs in 4% percent of chronic lymphocytic leukemia[ J]. Blood, 2008,112(Abstract) :42006.
  • 3Kakimoto T, Nakazato T, Hayashi R, et al. Bilateral occipital lobe invasion in chronic lymphocytic leukemia[ J]. J Clin Oncol, 2010,28(3) :30-32.
  • 4Saenz Frances F, Calvo Gonzalez C, Reche Frutgs J, et al. Bilateral papilledema secondary to chronic lymphocytic leukaemia [ J ]. Arch Soc Esp Oftalmo, 2007,82 ( 5 ) : 303- 306.
  • 5Kalac M, Suvic-Krizanic V, Ostojic S, et al. Central nervous system involvement of previously undiagnosed chronic lymphocytic leukemia in a patient with neuroborre- liosis[J]. Int J Hematol, 2007,85(4) :323-325.
  • 6Abedalthagafi M, Rushing E J, Garvin D, et al. Asymptomatic diffuse " encephalitic" cerebral toxoplasmosis in a patient with chronic lymphocytic leukemia: case report and review of the literature[J]. Int J Clin Exp Pathol, 2010,3 ( 1 ) :106-109.
  • 7Abbott B L. Chronic Lymphocytic Leukemia: Recent Advances in Diagnosis and Treatment [ J ]. Oncologist, 2006, 11(1) :21-30.
  • 8Caligaris Cappio F, Ghia P. Novel insights in chronic lymphocytic leukemia: Are we getting closer to understanding the pathogenesis of the disease? [ J]. J Clin Oncol, 2008. 26 ( 27 ) :4497-4502.
  • 9Vanura K, Le T, Esterbauer H, et al Autoimmune conditions and chronic infections in chronic lymphocytic leukemia patients at diagnosis are associated with unmutated IgVH genes [ J ]. Haematologica, 2008, 93 ( 12 ) : 1912- 1916.
  • 10李四强,刘伯英,田嘉玲,宫超.表现为溶血性贫血的慢性淋巴细胞白血病长期漏诊一例[J].临床误诊误治,2008,21(1):95-95. 被引量：1

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内科理论与实践
2009年 第4期

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