尿微量清蛋白测定在早期糖尿病肾病诊断中的临床价值

Clinical value of urinary mAlb detection in the diagnosis of early diabetic nephropathy

目的:探讨尿微量清蛋白(mAlb)检测在早期糖尿病肾病诊断中的临床价值。方法:应用散射比浊法对150例糖尿病患者和74例健康体检者的mAlb进行检测分析。检测数据用t检验进行统计学分析。结果:糖尿病组中尿mAlb含量与对照组比较,有非常显著性差异(P<0.01)。糖尿病患者中常规尿蛋白检测阳性组尿mAlb含量与常规尿蛋白检测阴性组比较,有非常显著性差异(P<0.01)。结论:尿mAlb可作为诊断糖尿病肾病和肾功能损伤的指标之一。

Objective： To explore the clinical value of urinary mAlb detection in the diagnosis of early diabetic nephropathy. Methods： The urinary mAlb of 150 patients with diabetes mellitus and 74 healthy people was detected by nephelometry. The data were analyzed by t test for statistical treatment. Results： Urinary mAlb content of diabetic group showed significant difference compared with that of the control group （P〈0.01）. In diabetic patients, urine mAlb content of positive conventional urine protein-positive group showed significant difference compared with conventional urine protein-negative group （P〈0.01）. Conclusion： mAlb can be used as one of the indicators for diagnosing diabetic nephropathy and renal injury.