雷米芬太尼复合丙泊酚与芬太尼复合羟丁酸钠诱导用于小儿有呼吸气管插管的比较

Comparative Remifentanil combined with Propofol and Fentanyl combined with Sodium oxybate for fentanyl-induced respiratory tracheal intubation in children

目的:观察雷米芬太尼复合丙泊酚与芬太尼复合羟丁酸钠在小儿麻醉慢诱导保留呼吸气管插管中的应用效果。方法:40例4～11岁ASAⅠ级的患儿,随机分为雷米芬太尼复合丙泊酚组(RF组)和芬太尼复合羟丁酸钠组(F组),两组均给予术前用药及局部表面麻醉,两组药物注射速度均大于60s,注药后90s由固定麻醉医师行气管插管,观察插管效果及对血流动力学的影响。结果:两组均能完成气管插管,RF组和F组插管满意率分别为80%和50%,RF组比F组插管时间明显缩短(P<0.01)。结论:在保留患儿呼吸的条件下进行气管插管,雷米芬太尼复合丙泊酚与芬太尼复合羟丁酸钠均能提供较好的气管插管条件,前者优于后者。

Objective： To observe the clinical effect of Propofol combined with Remifentanil and Sodium oxybate combined with Fentanyl in pediatric anesthesia induced by slow breathing to retain endotracheal intubation. Methods： 40 cases of 4- 11 year-old ASA I children were randomly divided into Remifentanil combined with Propofol group（RF group） and Sodium oxybate combined with Fentanyl group （F group）, two groups were given preoperative medication and local anesthesia, two groups of drug injection speed of more than 60 s, after injection anesthesiologists 90 s from fixed line tracheal intubation, observed the effect of intubation on hemodynamics. Results： The two groups were able to complete tracheal intubation, RF group and F group satisfied with the rate of intubation were 80% and 50%, RF group compared with the F group was significantly shorter intubation time （P〈0.01）. Conclusion： In children with respiratory conditions to retain under the tracheal intubation, Remifentanil combined with Propofol and Sodium oxybate combined with Fentanyl can provide better conditions for tracheal intubation, the former is superior to the latter.