新生儿缺氧缺血性脑病合并心肌损害71例临床分析

Clinical analysis of newborn with hypoxic-ischemic encephalopathy and myocardia damage

目的探讨新生儿缺氧缺血性脑病(HIE)合并心肌损害的临床特征及治疗体会。方法对71例HIE伴心肌损害的患儿出生后48h内进行心肌酶学测定,并做心电图检查。结果HIE患儿各有不同的临床表现,并有心肌酶谱各项指标不同程度增高及不同类型的心电图改变;病情愈重,血清心肌酶活性愈高,心电图异常率愈高。结论HIE患儿入院后应常规行心脏方面检测(心肌酶学、心电图),早期发现心肌损害,早期干预治疗。

ObjeCtive To evaluate the clinical characteristics and treatment experience of newborn with hypoxic - ischemic encephalopathy and myocardia damage. Methods Electrocardiograms were examined and myocardial enzymes were measured in 96 cases of neonatal hypoxic - ischemic encephalopathy with myocardial in jury with in first 48 hours of life. Results The 71 cases were found in various clinical manifestation with different level of myocardia enzymes increaseing and various kind of ECG changes. The more serious pathogenetic condition was, the higher myocardia enzymes will be, the higher abnormal electrocardiogram rate will be. Conclusio^n It is significant to carry out the early heart detection in newborn with HIE（ myocardial enzymes, electrocardiogram）. The myocardial injury should be interve -nted early.