高频振动流对机体血流分布的影响

The effect of high frequency vibration flow on the distribution of blood flow of organism

目的探讨高频率振动流对血流分布的影响。方法健康成年11只山羊通过高频率振动流人工心脏(vibrating flow pump,VFP),从左心尖将血液送至下行大动脉,取得了100%的辅助循环。测定上半身、下半身血流量的分配率。同时将机体血液循环视为电子回路,制作数学模型,从而计算出在15、20、25、30Hz的驱动状态下血管动态阻抗的曲线,找出动态阻抗与血流分配率的关系。结果四种驱动状态下的血管动态曲线高峰全部在30Hz附近,因此这种特性可以部分解释在驱动频率的30Hz时下半身血流量下降的原因。结论振动流通过改变频率,可影响血流分布,利用数学模型,计算得到的血管动态阻抗,能够表现曲线全体,充分显示了血管动态特性。

Objective To observe the effect of high frequency vibration flow on the distribution of blood flow of organism. Methods 11 healthy adult goats were operated by vibrating flow pump（VFP） to deliver blood from left cardiac apex to decent large arteries, which got 100% assisted circulation. The allocation ratio of upper half-body and lower half-body was measured. At the same time the blood circulation of organism was used as electricity circuit to make mathematic mode so as to calculate the curve of on-impedance of blood vessel at the driving state of 15,20,25,30Hz in order to find the correlation between on-impedance and allocation ratio of blood flow distribution ratio. Results The peaks of dynamic curve of blood vessel at the four kinds of driving states were all located about 30Hz ,so which could partly elucidate the reason why the volume of blood flow of lower half-body was decreased when driving ratio was 30Hz. Conclusion The vibration flow can affect the distribution of blood flow by change the vibration frequency, and the mathematic mode can be used to calculate the dynamic on impedance of blood vessel, which can display entire curve and show thoroughly the dynamic characteristics of blood vessel.