治疗抗生素相关腹泻268例的临床研究

Treatment of 268 cases of antibiotic-associated diarrhea in clinical research

目的分析医院感染抗生素相关性腹泻的发病情况，为临床制定有效、经济的治疗方法。方法将2003年1月～2008年12月医院感染抗生素相关性腹泻住院患者268例进行回顾性分析，分析抗生素相关性腹泻（AAD）的易患因素、抗生素使用情况以及治疗和转归。结果医院感染抗生素相关性腹泻多发生于老年人，抗生素使用时间〉5d，联合使用抗生素腹泻感染率较高。给予微生态制剂、小檗碱、制霉素治疗大多有效。结论如果患者使用抗生素期间或之后短时间内出现腹泻应考虑抗生素相关性腹泻。合理使用抗生素，严格控制广谱抗生素拓展抗生素相关性腹泻的治疗方法．

Objective Analysis of hospital infection of antibiotic-associated diarrhea incidence, clinical development of effective and economical method of treatment. Methods January 2003 - December 2008 nosocomial infection antibiotic-associated diarrhea patients were retrospectively 268 cases of analysis of antibiotic-associated diarrhea （AAD） of risk factors, antibiotic use, as well as treatment and prognosis. Results The hospital infection of antibiotic-associated diarrhea occur in the elderly, the use of antibiotics when the time is greater than five days, the joint use of antibiotics in higher rates of diarrhea. Given probiotics, small base, most effective in the treatment system. Conclusion If a patient during or after the use of antibiotics in a short period of time taking drug diarrhea antibiotic-associated diarrhea. Rational use of antibiotics, strict control of broad-spectrum antibiotics develop antibiotic-associated diarrhea treatment.