干扰素在乙肝病毒治疗中的应用分析

Interferon treatment of hepatitis B virus in the application of analysis

目的探讨干扰素α-2b对乙型病毒性肝炎的临床治疗效果。方法将120例乙型肝炎患者随机分为治疗组和对照组。对照组给于常规治疗,治疗组在此基础上给予干扰素α-2b联合治疗,疗程均为3个月。观察两组在治疗结束后进行肝功能、乙肝病毒血清学指标和不良反应的比较。结果治疗组在改善肝功能方面和乙肝病毒血清学指标均优于对照组,不良反应发生情况两组之间差异无统计学意义。结论干扰素α-2b在促进乙肝病毒的肝功能恢复和乙肝病毒血清学指标方面具有肯定疗效,无明显不良反应,值得临床推广。

Objective To find the clinical treatment of hepatitis B virus with interferon α-2 b. Methods 120 cases of hepatitis B patients were randomly divided into treatment-group and control group. In the control group to conventional therapy, the treatment group on the basis of this to the interferon α-2 b in the treatment, are three-month course of treatment. It was observed at the end of treatment after liver function, serum HBV indicators and comparison of adverse reactions. Results Group to improve the treatment of liver function and hepatitis B virus serum indicators are better than the control group,the occurrence of adverse reactions between the two groups no significant difference. Conclusion Interferon α-2 b in the promotion of the hepatitis B virus liver function and hepatitis B virus serum indicators are certainly effect, no significant side effects,it is clinical.