阿奇霉素治疗支原体肺炎患儿前后血清PCT和CRP测定的临床意义

Clinical significance of changes of PCT,CRP serum levels after azithromycin treatment in children with myeoplusmalpneumoma

目的探讨支原体肺炎患儿血清中降钙索原（PCT）和C反应蛋（CRP）水平的变化及意义。方法分别应用放免法和免疫法测定了30例支原体肺炎患儿血清中PCT和CRP，并与26例正常儿作比较。结果在治疗前血清PCT和CRP水平高于正常儿组（P〈0．01—0．001），治疗后与正常儿组比较差异无统计学意义（P〉0．05）。结论测定支气管肺炎患儿血清中PCT和CRP水平对疾病的治疗和预后有十分重要的临床价值。

Objective To investigate the changes of PCT, CRP serum levels after treatment in children with myeoplusmalpneumoma. Methods The senm level of PCT was measured with RIA, and CRP with immunological method both before and after treatment in 30 children with myeoplusmalpneumoma and 26 healthy controls. Results Before treatment the serum levels of PCT, CRP were significantly higher than those in controls （P〈0. 001 ）. One week after completion of treatment, PCT and CRP levels returned to normal with no significant diference from those in the controls （ P〉0. 05 ）. Conclusion Determination ofPCT, CRP levels is clinically useful in the management of myeoplusmalpneumoma in children.