用于荧光免疫光纤生物传感器中信号分析的理论模型

Theoretical Model Used for the Analysis of the Signal of Fluorimmunoassays Fiber-Optic Biosensor

利用多层介质中偶极子辐射理论,得到了荧光免疫光纤生物传感器的初始荧光分布.在此基础上,利用几何光波导理论给出了荧光信号在光纤探针中的传输模型.通过定义光纤探针的耦合效率、传输效率、收集效率和有效收集效率等概念,实现了对基于倏逝波激发的荧光免疫光纤生物传感器系统中荧光信号的跟踪分析.并建立了理论模型,可用于该类传感器系统的优化设计.

Using the theory of radiation of dipoles placed within a multilayer system, the original distribution of fluorescence of flour-immunoassays fiber optic biosensor is presented. The transmission model of fluorescence signal is achieved by using the classical geometric optical waveguide theory. After introducing the Coupling Efficiency,the Transporting Efficiency,the Collecting Efficiency and the Effective Collecting Efficiency,the analysis of fluorescence signal of the fiber-optic biosensor based on evanescent wave is realized. The model is helpful to optimization of the system of such kind.