期刊文献+

孕早中期C反应蛋白水平及其与妊娠期糖尿病的关系

下载PDF
导出
摘要 目的观察孕早中期C反应蛋白(CRP)水平及其与妊娠期糖尿病(GDM)的关系。方法31例GDM患者、33例糖耐量减低(IGT)患者与44例无糖耐量减低正常妊娠妇女,分别于孕10~14周和孕24~28周行CRP检测,比较三组的CRP水平。结果三组孕妇的孕早、中期血清CRP水平差异均有统计学意义(<0.05),GDM组高于IGT组,IGT组高于NGT组。各组孕中期的CRP水平高于孕早期,差异均有统计学意义(<0.01)。结论GDM的发展过程中伴随有慢性炎症反应,且这种炎症反应随着妊娠进展和糖耐量异常的加重更为明显。孕早期血清CRP监测有利于GDM的早期发现和预防。
出处 《现代实用医学》 2009年第5期483-483,490,共2页 Modern Practical Medicine
  • 相关文献

参考文献2

二级参考文献30

  • 1RidkerPM,BuringJE,Cook NR,et al.C-reactiveprotein,the metabolic syndrome,and risk of incident cardiovascular events:an 8-year follow-up of 14 719 initially healthy American women.Circulation,2003,107(3):391-397.
  • 2Thorand B,Lowel H,Schneider A,et al.C-reactive protein as a predictor for incident diabetes mellitus among middle-aged men:results from the MONICA Augsburg cohort study,1984-1998.Arch Inter Med,2003,163(1):93-99.
  • 3Lee WY,Park JS,Noh SY,et al.C-reactive protein concentrations are related to insulin resistance and metabolic syndrome as defined by the ATP Ⅲ report.Int J Cardiol,2004,97(1):101-106.
  • 4Aronson D,Sella R,Sheikh-Ahmad M,et al.The association between cardiorespiratory fitness and C-reactive protein in subjects with the metabolic syndrome.J Am Coll Cardiol,2004,44(10):2003-2007.
  • 5Yudkin JS,Juhan-Vague I,Hawe E,et al.Low-grade inflammation may play a role in the etiology of the metabolic syndrome in patients.with coronary heart disease:the HIFMECH study.Metabolism,2004,53(7):852-857.
  • 6Recasens M,Lopez-Bermejo A,Ricart W,et al.An Inflammation Score is better Associated with Basal than Stimulated Surrogate Indexes of Insulin Resistance.J Clin Endocrinol Metab,2005,90(1):112-116.
  • 7Nesto R.C-reactive protein,its role in inflammation,Type 2 diabetes and cardiovascular disease,and the effects of insulin-sensitizing treatment with thiazolidinediones.Diabet Med,2004,21(8):810-817.
  • 8Leinonen A,Hiilesmaa V,Andersen H,et al.Diurnal blood glucose profiles in women with gestational iabetes with or without hypertension.Diabet Med,2004,21(11):1181-1184.
  • 9Kopp W.Role of high-insulinogenic nutrition in the etiology of gestational diabetes mellitus.Med Hypotheses,2005,64(1):101-103.
  • 10Kuribayashi T,Shimada T,Matsumoto M.Determination of serum C-reactive protein (CRP) in healthy beagle dogs ofvarious ages and pregnant beagle dogs.Exp Anim,2003,52(5):387-390.

共引文献32

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部