两面针中一个新的苯并菲啶类生物碱(英文)

A New Benzophenanthridine Alkaloid from Zanthoxylum nitidum

目的:研究两面针[Zanthoxylum nitidum(Roxb.)DC.]根和茎的化学成分。方法:采用硅胶柱层析及Sephadex LH-20等色谱技术分离并纯化化合物,根据理化性质及波谱技术进行鉴定结构。结果:从两面针根和茎的乙醇提取物中分离得到两个苯并菲啶类生物碱,分别命名为:8-(2'-环己酮)-7,8-二氢白屈菜红碱(1)和8-(1'-羟基乙基)-7,8-二氢白屈菜红碱(2)。结论:化合物1为新化合物。

AIM： To study the chemical constituents of the roots and stems of Zanthoxylum nitidum （Roxb.） DC.. METHODS： Silica gel and Sephadex LH-20 column chromatography were used to isolate and purify the constituents. Various spectroscopic analyses were involved to elucidate the structures. RESULTS： Two benzo[c]-phenanthridine alkaloids, named 8-（2＇-cyclohexanone）-7, 8-dihydrochelerythrine （1） along with a known compound 8-（1＇-hydroxyethyl）-7, 8-dihydrochelerythrine （2） were isolated from this plant. CONCLUSION： Compound 1 was a new compound.