不同血压水平与血肌酐相关性的研究

Investigation on the correlation between people with different blood pressure levels,metabolic syndrome and plasma creatinine levels

目的研究中老年人群不同血压水平与血肌酐的相关性。方法对744例年度体检人员按不同年龄分为5组,分析血压水平、体质量指数、三酰甘油、高密度脂蛋白胆固醇及血糖的变化规律;不同血压水平对血浆肌酐的影响。结果(1)744例体检人员中代谢综合征(MS)的患病率为32.9%;(2)血糖异常、高血压、超重/肥胖及血脂异常的患病率分别为17.5%、71.8%、53.8%和58.1%;(3)高血压病患者血浆肌酐水平与正常血压及正常高值血压者相比明显升高(P<0.01或<0.05)。结论中老年人群MS患病率较高,血压升高与肾功能减退密切相关,应及时干预。

Objective To investigate the correlation among different blood pressure levels, metabolic syndrome and plasma creatinine levels in the middle-aged and elderly people. Methods 744 individuals were divided into 5 different age groups; blood pressure levels, body mass index （ BMI）, triglyceride, high-density-lipoprotein cholesterol,blood glucose were measured in 744 individuals. Results （ 1 ） The morbidity of MS was 32.9%. （2） The prevalence of glucose metabolic disorder accounted for 17.5 %, The morbidities of hypertension, overweight or obesity, lipid metabolic disorder were 71.8% ,53.8 %, and 58. 1% respectively. （3）The morbidity of MS and the plasma creatinine levels were significantly higher in patients with hypertension than those in normal control. Conclusion The prevalence of MS is relatively higher among the middle-aged and elder people. Intervention should be provided to prevent it timely.