针灸治疗抑郁性神经症临床随机对照试验的质量评价

Quality Evaluation with randomized controlled trials on Acupuncture and Moxibustion Treating Depressive Neurosis

目的评价国内针灸治疗抑郁性神经症的临床随机对照试验的真实性和相关内容。为提高研究者临床研究设计水平和质量提供理论依据。方法全面广泛收集相关文献，按照临床流行病学和循证医学的原则，采用统一编制的“针灸治疗抑郁性神经症文献质量评价信息采集表”，对1980-2008年发表的临床随机对照试验进行质量评价。结果符合纳排标准的共15篇，均发表在2000年以后。其中正确使用随机方法的5篇（33-3％），采用诊断标准的10篇（66．6％），叙述排除标准的10篇（66．6％），有疗效判定标准的12篇（80％），采用盲法的4篇（26．7％），报告病例退出的5篇（33．3％），报告疗效统计学方法的9篇（60％），都没有进行样本估算和随访情况的描述。结论针灸治疗抑郁性神经症临床研究文献近年来更多采用了随机对照方法，但亦存在不足。

Objective To assess the current situation and quality of clinical randomized controlled trials（RCTs） designed for accessing the treatment of depressive neurosis with acupuncture and moxibustion. Methods Relative clinical research literatures published from year 1980 to 2008 were collected, and composed into ＂evaluation to all literature of acupuncture and moxibustion treating depressive neurosis message table＂, according to the clinical epidemic disease and EBM. The quality evaluation on these trails were performed. Results There were altogether 15 articles included in this study. Among them, 5 articles used the correct randomized controlled trials （33.3%）, 10 articles used the diagnostic criteria （66.6%）, 10 articles used excluded criteria （66.6%）, 12 articles used the therapeutic evaluation criteria （80%）, 4 articles used blind trials （26.7%）, 5 articles reported quit cases（33.3%）, and 9 articles reported the adopted statistical methods（60%）4 articles Conclusion The quality of RCT of acupuncture and moxibustion for depressive neurosis needs to be improved.