放射性粒子近距离治疗软组织肉瘤研究进展

Research progress of brachytnerapy in soft tissue sarcoma

近距离放疗以其独特的放射生物学及放射物理学特性成为软组织肉瘤治疗的重要手段，根据治疗时机分为术前放疗、术中放疗、术后放疗、单纯放疗，在提高患肢保存率及肉瘤局部控制率方面发挥了重要作用，但对治疗时机、治疗方式、植入剂量的选择仍存在争议。

Brachytherapy has become an important treatment for soft tissue sarcoma by its unique radiobiology and radiation physics characteristics, the treatment time is divided in accordance with preoperative brachytherapy, intraoperative brachytherapy, postoperative brachytherapy, brachytherapy alone, which in improving the rate of limb preservation and local control rate sarcoma has played an important role. However, the timing of treatment, treatment modalities, the choice of implantation dose is still in dispute.