宫颈上皮内瘤变Ⅰ级的自然转归与随访观察

The Natural Prognosis and Follow-up of CINⅠ

目的探讨CINⅠ患者的自然转归。方法以组织病理学检查诊断为CINⅠ患者74例作为观察对象,随访12个月后行HR-HPV、TCT检查;随访24个月后行HR-HPV、TCT、电子阴道镜及组织病理学检查。结果74例CINⅠ患者随访24个月后,自然消退42例(56.76%),病变持续25例(33.78%),进展7例(9.46%),其中宫颈上皮内瘤变2级(CINⅡ)5例,宫颈上皮内瘤变3级(CINⅢ)2例。结论HR-HPV及TCT可以作为CINⅠ病变转归的监测方法。

Objective CIN I patients were followed for 12 and 24 months to study the natural history of CIN I. Methods 74 cases with pathologically diagnosed CIN I were examined repeatedly in the 12th and 24th months. The primary follow - up was on the twelfth month after sceening including HR -HPV and TCT;The second follow -up was on the twenty -fourth month after screening including HR - HPV, TCT, colposcopy and histopathology examination. Results After twenty - four months follow - up, the rate of regression was 56.76% and the rate of persistence is 33.78%. 9.46% patients had progressed diseases, including 5 progressed to CIN II and 2 progressed to CIN III. Conclusion HR - HPV and TCT can be the monitoring method of CIN I.