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辛伐他汀治疗心律失常的临床疗效观察 被引量:7

Evaluation of Curative Effect of Simvastatin for Arrhythmia
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摘要 目的观察辛伐他汀(舒降之)治疗心律失常的临床疗效。方法将84例心律失常患者随机分为两组:治疗组42例,对照组42例。两组常规给予美托洛尔,治疗组给予辛伐他汀20mgqn。使用12导联同步心电图和24h动态心电图检查两组变化情况,3月为1疗程。结果治疗组心律失常症状改善有效率(73.8%)明显高于对照组(47.6%,P<0.05)。结论辛伐他汀治疗心律失常有良好治疗作用,值得进一步探索研究。 Objective To evaluate the clinical efficacy of Simvastatin(zocor) in treating various arrhythmias. Methods 84 patients with arrhythmia were randomly divided into control group ( n-42 ) and the Simvastatin group ( n = 42 ). The both groups received conventional administration with Metoprolol, while the treatment group with Simvastatin 20mg qn addtionally. 12 lead ECG and the Hoter was used to monitor the changes of heart rate and rhythm of patients. The clinical symptoms and signs of patients were also observed at the same time. The course of treatment was 3 months. Results The total effective rate in treatment group was significantly higher than that in control group ( 73.8% vs 47.6%, P 〈 0.05 ). Conclusion The clinical curative effect of Simvastatin was better for various arrhythmia, and deserves further clinical applications.
出处 《中华全科医学》 2009年第9期958-960,共3页 Chinese Journal of General Practice
关键词 辛伐他汀 心律失常 心电图 Simvastatin Arrhythmia ECG
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