硒及其化合物与胃癌研究进展

Advance in Relationship between Gastric Carcinoma and Selenium or Selenide

胃癌是全世界发病率和死亡率仅次于肺癌的恶性肿瘤,而我国是世界上胃癌发病率最高的国家之一。大量的研究资料表明,硒及其化合物具有广泛的生物学作用,具有阻止多种肿瘤发生发展的作用,硒与胃癌之间有着较大的关联性,但两者之间的关系尚不明确。为更好地认识硒及其化合物对胃癌发生发展的影响,进一步了解两者之间的关系以及可能的作用机制,本文就近年来相关的研究进行综述。

Gastric carcinoma is one of the most common malignant tumor in the world, its incidence and mortality are second only to lung cancer,and China owns its highest incidence now. Many studies have shown that selenium and its chemical compounds have wide biological action and can stop the existence and deterioration of varied tumors. There may be some considerable relations between selenium and gastric carcinoma, yet not clear and definite. So to have a better understanding to this and make further improvements to clarify relations between the two and their possible function mechanism, this article will summarize relative studies in recent years.