高血压脑出血术后D-二聚体动态变化的临床研究

Analysison D-dimer for the Patients after Cerebral Surgery Operation

目的研究高血压脑出血术后患者血液中D-二聚体的动态变化与病情程度及预后的关系。方法采用磁珠法对89例高血压性脑出血术后患者的血浆D-二聚体水平进行检测,与36例健康体检者进行对照,并分析其与病情、预后的关系。结果各型脑出血患者血浆D-二聚体含量间差异有统计学意义(P<0.01)。好转组与无好转组D-二聚体异常率间差异有统计学意义(P<0.01)。结论动态观察D-二聚体的变化对高血压性脑出血术后的病程、病情判定及评价预后有重要意义,是判断高血压脑出血术后患者病情程度及预后情况的有效指标之一。

Objective To explore the relationships between the levels of D - dimeride and the patient＇s condition and prognosis in the patients after cerebral hemorrhage of hypertension surgery operation. Methods 89 blood samples of the patients after cerebral surgery operation were obtained for testing D - dimeride assay. Then analyzed assay results statistically and also D - dimeride assay of 36 health adults, and analyzed the relationships between D - dimeride assay levels and the severity of disease as well as outcome. Results Levels of D - dimeride were significantly higher than those in control group （ P 〈 0. 01 ）, in cerebral hemorrhage of hypertension surgery operation, levels of D - dimeride varied significantly as the pathogenetic condition varied from being light, medium to severe （ P 〈 0.01 ）. Conclusion levels of D - dimeride were closely related to the onset. development and prognosis of cerebral hemorrhage of hypertension, therefore were helpfuo in evaluating the pathogenetic condition and the prognosis in cerebral hemorrhage of hypertension surgery operation.